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Types
of Nipple Discharge
Nipple discharge is the production of fluid from the nipple. The
fluid comes from the milk gland ducts that open at the nipple. Most
cases of nipple discharge are due to normal, benign conditions and
are usually hormone-related. Approximately one third of all women
can produce a nipple discharge by gently massaging their breasts.
This 'innocent' nipple discharge usually comes from multiple ducts
in both breasts in pre-menopausal women. Bloodstained discharge
from a single duct in one breast can be sinister in nature and may
represent an underlying carcinoma.
What Do I Do if I Have Nipple Discharge?

Women with nipple discharge should consult their family doctor without
delay. They may then be referred to a breast specialist who will
examine the breasts in more detail. Depending on the number of discharging
ducts and the colour of the discharge produced, the specialist may
arrange further investigations including microscopic examination
of the discharge fluid, an ultrasound scan (if the patient is younger
than 35 years) and/or a mammogram (if the patient is older than
35 years).
Occasionally a breast lump is found in a patient presenting with
nipple discharge. Such lumps are investigated appropriately. If
the microscopic examination and mammography/ultrasound show no worrying
features, the patient can then be reassured. Women with blood-stained
discharge coming from a single milk gland duct, and showing abnormalities
on microscopic examination, will require surgical excision of the
discharging duct. The operation to removing a single duct is known
as a microdochectomy and is usually performed as a day-case. The
removed tissue is sent to the pathology laboratory for further examination.
In some centres it is also possible to carry out a camera examination
of the nipple duct, which is called mammary ductoscopy. The author
has recently introduced this new technology into his practice (Figure
14).
Clear discharge arising from multiple milk gland ducts is usually
normal. It does not require treatment unless it becomes troublesome
or associated with abnormal microscopy or mammography, when surgery
may be considered. The operation consists of the total removal of
all the ducts draining into the nipple. The main risks of the procedure
include the death of the nipple tissue (uncommon) and the reduced
sensitivity of the nipple area (in one third of cases). Such complications
should be weighed against the severity and inconvenience of the
symptoms.

What Does a Milky Discharge Mean?
Milky discharge through the nipple, called galactorrhoea, is normal
during and within 2 years after pregnancy. Milky discharge occurring
outside pregnancy can be caused by an imbalance of the hormone prolactin,
which controls milk production. A small gland in the brain called
the pituitary gland produces prolactin. Tumours arising in this
gland may cause excessive amounts of prolactin to be released into
the bloodstream, thus stimulating the breast tissue to release a
milky discharge. A brain scan may be required to look for tumours
in the pituitary gland. Pituitary tumours are usually benign and
are easily treated with drugs or by surgery. If prolactin levels
are within normal limits, the patient can be reassured that the
discharge is likely to improve without further intervention.
Other Causes of Nipple Discharge
| Inflammation
and dilatation of the nipple duct |
Benign
tumour of the nipple duct
|
Breast
cancer
|
Called
periductal mastitis/duct ectasia
Pain and nipple inversion are common
More common in smokers
Improved by stopping smoking and by antibiotics
Surgery if persistent
|
Called
intraductal papilloma
Single-duct blood-stained discharge
Treated by surgical removal
No follow-up is required
|
Non-invasive
(DCIS) type
Does not usually spread
Mastectomy is required as it is close to the nipple
Surgical treatment is curative (98%)
|

Breast Ductoscopy under
Local Anaesthesia

Breast Ductoscopy
under Local Anaesthesia
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